MONDAY, March 12, 2018 -- Older adults who are sleepy during the day might have harmful plaque building in their brain that is a sign of impending Alzheimer's disease, researchers report.
A hallmark of Alzheimer's is the accumulation of a protein in the brain called beta-amyloid. It's believed that one benefit of sleep is to clear beta-amyloid, and poor sleep might allow it to build up, the authors of the new study pointed out.
WEDNESDAY, Feb. 14, 2018 -- Brain plaques believed to contribute to Alzheimer's disease melt away in mice when robbed of a key enzyme, researchers report.
And the rodents' intellectual function actually improved as their amyloid plaques dissolved from lack of beta-secretase (BACE1), an enzyme critical in the formation of the plaques, said senior researcher Riqiang Yan. He is vice chair of neuroscience with the Cleveland Clinic Lerner Research Institute.
TUESDAY, Jan. 30, 2018 -- Stimulating the brain with an implantable device may be safe -- and possibly helpful -- for some people with Alzheimer's disease, a small pilot study suggests.
In what researchers described as a "proof of concept" treatment, three Alzheimer's patients had deep brain stimulation (DBS) wires implanted in the brain -- in areas related to skills like planning, judgment and problem-solving.
THURSDAY, Jan. 25, 2018 -- As more experimental drugs fail to stop Alzheimer's from destroying human memory, experts now wonder whether research into the devastating brain disease has been marching in the wrong direction.
In recent weeks, a pair of high-profile disappointments have been reported, including one just announced on a trial of the Eli Lily drug solanezumab.